Plaque formation inside blood vessels begins when the inner lining becomes irritated by high cholesterol, smoking, high blood pressure, or inflammation. The inner lining is a thin layer of cells called the endothelium. When it becomes stressed, tiny openings form that allow cholesterol rich particles to slip beneath the surface. These particles settle in the vessel wall where they become oxidized. Oxidized particles trigger an immune reaction that attracts white blood cells. The white blood cell
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The inner lining of blood vessels, called the endothelium, controls blood flow, clot prevention, and vessel flexibility. Chronic stress exposes this lining to repeated surges of stress hormones and inflammatory signals. These chemicals were designed for short emergencies, not constant exposure. Over time, stress hormones increase oxidative damage and reduce nitric oxide production, a substance essential for vessel relaxation. The endothelial surface becomes less smooth and less responsive. This
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