Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The Detroit Lions and the San Francisco 49ers will go head to head for Monday Night Football this week, but tight end George Kittle is kicking things off with nothing but love, at least as it relates ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

It's a recipe that's as versatile as it is simple. Pair it with tortilla chips, quesadillas, tacos — whatever you want on ...

Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Find out what the San Francisco 49ers are saying as they prepare for their Week 17 matchup vs. the Detroit Lions.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...

Winters (chest) was a full participant in Thursday's practice. Winters picked up a chest issue in Sunday's loss to Miami, but his ability to practice in full Thursday suggests that he's not ...