A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation, which ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Transfer RNA, more commonly referred to as tRNA, is well known for its key role in translating genetic material into protein. Recent discoveries about fragments of tRNA, which scientists had ...

IRE1α-driven production of 5’-tRH-Gly GCC during ER stress, aiding cellular adaptation in various eukaryotic organisms, ranging from yeast to humans To fill this knowledge gap, a group of researchers ...

An abnormal epigenetic modification of RNA could be related to senescence and aging disorders, pointing towards the enzyme methyltransferase-like 1 (METTL1) as a potential therapeutic target.

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...

Initially dismissed as a wealthy and frivolous socialite, Charles Swann in Marcel Proust’s “In Search of Lost Time” eventually transforms from a minor figure to an important one. Were biology a novel, ...

In 2020, Juan Alfonzo, a professor of molecular biology, cell biology and biochemistry, began a project out of “pure COVID boredom.” Now, that project may become the largest scientific undertaking ...

In recent years, drug discovery has become a search for targets that take the form of gene-expression differences between normal and disease states. One of the leading approaches has been based on ...