The San Francisco 49ers take on the Tennessee Titans on Sunday, Dec. 14 at 1:25 p.m. PDT at Levi’s Stadium.

The depth of the San Francisco 49ers, especially on defense, is insanely thin. They cannot afford to have a few players or ...

The San Francisco 49ers put up a “help wanted” sign for their pass-rushing unit the moment Nick Bosa was lost for the season.

A gas explosion set off a major fire in a San Francisco Bay Area neighborhood on Thursday after obliterating at least one ...

Fire officials say six people have been taken to hospitals after a gas explosion started a major fire in a San Francisco Bay ...

A gas explosion set off a major fire in a San Francisco Bay Area neighborhood on Thursday after obliterating at least one ...

These AI startups founded by bright young minds in their teens and early 20s are disrupting industries and attracting top ...

The lawsuit is the first wrongful death litigation involving an AI chatbot that has targeted Microsoft, and the first to tie ...

It looks like the San Francisco 49ers are set to face Philip Rivers in Week 15 against the Indianapolis Colts. The last time ...

Get full details for 49ers vs. Titans in Week 15—start time, TV channel, streaming options, odds, and radio coverage for San ...