For decades, scientists have measured how specific regions of the brain shrink with age and disease. Other studies have tracked widening sulci or enlarging ventricles. But is parenchymal shrinkage the ...
Scientists have uncovered a potential new mechanism whereby α-synuclein pathology spreads. Like black holes, large densities of α-synuclein pull in surrounding matter. Among the victims trapped in ...
Polluted air leaves its mark on the brain. In the September 8 JAMA Neurology, Edward Lee and colleagues at the University of Pennsylvania, Philadelphia, report that two decades of autopsies reveal a ...
Antisense oligonucleotides have emerged as a promising approach for treating neurodegenerative disease. They can dial down toxic proteins or help restore functional ones, and have been approved for ...
As the brain ages, many cell types succumb to senescence. How does this start? In the September 10 Nature Aging, scientists led by Wei Cai, Zhengqi Lu, and Quentin Liu at Sun Yat-Sen University, ...
This interactive resource organizes decades of data on biomarkers for Alzheimer's disease. Biomarker measurements from the cerebrospinal fluid and blood are curated from the primary literature and ...
Contact Information Edward Lee, M.S. TaipeiProfessional Information Ph.D. candidateAcademic Sinica ...
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