Introduction Cardiopulmonary exercise testing (CPET) is shown to be feasible in patients with interstitial lung disease (ILD), highlighting its prospective use as an outcome measure for prognostic ...

Statins reduce cholesterol levels by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and have an established role in the treatment of atherosclerotic disease. Recent research has ...

Analysis of airflow in the terminal portion of the maximal expiratory flow volume curve has been suggested as a useful test for the early diagnosis of chronic airways obstruction. Whether such an ...

Pulmonary rehabilitation has established itself as a vital and core therapy for people with chronic lung disease. Significant improvements are seen in several patient outcomes, for the thousands ...

We present the case of a 45-year-old man who reported 2 years of cough and expectoration and 1 year of dyspnoea. He had a history of dry nasal snuff inhalation 15 times/day for 10 years, worked as a ...

Cook and Strachan are to be congratulated on their series of meta-analyses on the health effects of passive smoking. However, in their analysis of parental smoking and spirometric indices they gave as ...

Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic lung disease and predisposes individuals to acute lung injury and pulmonary infection. Alveolar macrophages are ...

Rationale Pulmonary rehabilitation (PR) is an effective, key standard treatment for people with COPD. Nevertheless, low participant uptake, insufficient attendance and high drop-out rates are reported ...

Background The National Early Warning Score 2 (NEWS2) includes two oxygen saturation scales; the second adjusts target saturations to 88%–92% for those with hypercapnic respiratory failure. Using this ...

Cyclo-oxygenase (COX), also known as prostaglandin H synthase (PGHS), is the rate limiting enzyme for the conversion of arachidonic acid to prostanoids and exists in two isoforms. COX-1 is ...

Background This study aimed to evaluate whether incidental CT findings of emphysema, airway thickening and bronchiectasis, as seen on CT scans performed for other non-pulmonary clinical indications, ...

Background: A study was undertaken to evaluate exacerbations and their impact on the health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD). Methods: A 2 ...