NDA for icotrokinra for the treatment of adults and adolescents 12 years of age and older with moderate to severe plaque ...

Investigational icotrokinra is the first targeted oral peptide designed to selectively block the IL-23 receptor, 14 which underpins the inflammatory response in moderate-to-severe plaque PsO ...

Icotrokinra demonstrated a favorable safety profile, with 50% of adolescents treated with icotrokinra experienced ≥1 adverse event (AE), compared to 73% of adolescents receiving placebo at 16 weeks.