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Rams vs. 49ers predictions, odds, time: 2025 NFL Week 5 Thursday Night Football picks by advanced model

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Niners Wire · 29d

What TV channel is 49ers vs. Rams on today? Time, TV schedule for NFL Week 5 game

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NFL 2025 Week 9 odds: Rams vs. Saints spread, line, over/under

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49ers vs. Giants prediction, pick, odds for Sunday's NFL Week 9 game - 11/2/2025

The San Francisco 49ers (5-3) go on the road to take on the New York Giants (2-6) at MetLife Stadium on Sunday, November 2, 2025.

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NFL Week 9 staff picks: Moneyline, spread, over/under predictions

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Ravens vs. Dolphins prediction: ‘Thursday Night Football’ Week 9 picks, odds, props

· 16h

NFL Predictions: 3 Plus Money Bets to Target for Week 9

Tucker could emerge as a key target in this offense coming off the bye.

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NFL Week 9 Game Picks

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NFL Player Prop Picks: Week 9 Best Bets

49ers finally get some good news at QB

Digest more

· 13h · on MSN

49ers Provide Update on Brock Purdy’s Delayed Return

Following their Week 1 win over the Seattle Seahawks, he was diagnosed with turf toe, and while he returned for Week 4, he has missed every other game so far this year.

Niners Wire · 8h

49ers finally get some good news at QB with Brock Purdy's improved status for Week 9

· 8h

Mac Jones will start at QB for 49ers vs. Giants; Brock Purdy questionable

Thu.’s Saints vs Rams injury report

Digest more

· 1d

NFL Week 9 preview: Saints vs. Rams

Tyler Shough now is the starter for the Saints, replacing Spencer Rattler, and he faces a stiff test in his first start against the Rams. Chris Simms and Mike Florio don't think it'll be close in favor of Los Angeles.

SB Nation on MSN · 8h

Should Rams consider resting key injured starters vs. Saints?

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Thursday’s Saints vs. Rams injury report

Rams Wire

Here's which uniforms the Rams and 49ers are wearing on Thursday night

The Rams are rocking a uniform combination that they haven't worn yet this season, while the 49ers will be in their traditional white jerseys.

29d

Rams vs. 49ers prediction: High-octane L.A. offense looking to keep rolling against banged-up San Francisco

The NFC West is a crowded race to start the 2025 NFL season, as expected, but two of the teams atop the division are in very different places. Both the Los Angeles Rams and San Francisco 49ers sport 3-1 records entering Week 5, which they'll kick off on "Thursday Night Football." Yet only one is operating with momentum.

28d

Rams vs. 49ers score, takeaways as Mac Jones, San Francisco pull off TNF stunner

The 49ers took down the Rams in overtime in their Week 5 "Thursday Night Football" matchup. Here's how it happened.

29d

49ers vs. Rams predictions, picks and best bets for NFL Thursday Night Football: NFC West rivalry in primetime

These coaches are friends who joined the division at the same time, are considered offensive geniuses and have had successful tenures as coaches of their respective teams. When they meet on NFL Thursday Night Football, McVay’s Rams are in much better shape when it comes to team health and availability.

Rams Wire

What channel is Rams vs. 49ers on today? Time, TV schedule to watch Week 5 game

The Rams are back on the field tonight just days after beating the Colts, hosting the 49ers at SoFi Stadium for a big Week 5 matchup.

29d

49ers vs. Rams on Thursday Night Football: Inactives, news, live updates as Niners battle for NFC West lead without Brock Purdy, Ricky Pearsall, George Kittle

Thursday Night Football for Week 5 renews an NFC West rivalry when the San Francisco 49ers head south to take on the Los Angeles Rams. These teams have dominated the division since 2017, winning seven of the last eight division titles combined. The 2017 season was also the first of Kyle Shanahan's and Sean McVay's tenures.

8hon MSN

Rams’ rookie does best Sean McVay impression for Halloween

The post Rams’ rookie does best Sean McVay impression for Halloween appeared first on ClutchPoints.

Yardbarker on MSN

Trade Rumors: 49ers, Cowboys, Rams

HC Kyle Shanahan on QB Brock Purdy‘s toe recovery and if he was where the team expected him to be: “Yes. It’s different dealing with a toe but I’d say it’s steadily getting better each week.” (Nick Wagoner) 49ers GM John Lynch talked about Purdy’s status: “We’re taking the appropriate measures.