MedPage Today

Endocrine Therapy Resistance in HR+/HER2- Breast Cancer: A Common Clinical Challenge

Endocrine therapy typically slows cell cycle progression by reducing cyclin D1, which partners with CDK4/6 to promote cell ...
Fitgurú on MSN

The 6 Anti-Inflammatory Superfoods That Powerfully Outperform Ibuprofen

Chronic inflammation is the silent epidemic sweeping America. It’s not just the sharp pain of arthritis; it's the root cause ...
The EMBO Journal

Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastomas (GBM) are treated with high ...
Frontiers

Centella asiatica enhances diabetic wound healing by decreasing macrophage-driven inflammation via the AKT/MAPK/NF-κB pathway

We obtained mouse mononuclear macrophage cells (RAW 264.7) from Procell Company (Wuhan, China). These cells were cultured in RPMI 1640 medium with 11.1 mM glucose (Gibco, 12633012) at 37 °C in a ...
C&EN

Gambogic Acid Inhibits MDCK Cyst Enlargement by Suppressing Inflammation via p38 and NF-κB Pathway Inhibition

Biomedical Science Program, College of Medicine and Public Health, Ubon Ratchathani University, Warin Chamrap, Ubon Ratchathani 34190, Thailand ...
Frontiers

Radix Pseudostellaria polysaccharides alleviate sepsis-induced liver injury by modulating the gut microbiota via the TLR4/NF-κB pathway

Background: Sepsis-induced liver injury (SLI) is a life-threatening complication with limited therapeutic options. Radix Pseudostellariae polysaccharides (RPPS), a component of traditional Chinese ...