Key protein can restore aging neural stem cells' ability to regenerate

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that a key ...
News-Medical.Net on MSN

Ageing slows brain protein clearance and shifts synaptic waste to microglia

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
News-Medical.Net on MSN

Sperm RNA aging shift that may explain paternal age effects

By Dr. Priyom Bose, Ph.D. A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the ...
Frontiers

Multi-omics Strategy Reveals Natural Sources as Potential Therapeutic Agents against Type-II Diabetes in the Aging Population

Type 2 diabetes (T2D) is a major chronic metabolic disease worldwide and is especially prevalent in older adults. Although many synthetic drugs are ...
eLife

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...