A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Chemistry researchers at the University of Utah have uncovered an enzyme, dubbed PapB, that can "tie off" therapeutic ...

Researchers at Karolinska Institutet have discovered how cells can adjust their gene activity to survive when oxygen runs low ...

CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

Scientists at the University of Duisburg-Essen are researching new therapies for aggressive forms of childhood leukaemia. For the first time, their ...

GLP-1–pathway agonists such as semaglutide and newer multi-agonists have transformed care for obesity and diabetes, yet developers still wrestle with durability, tissue targeting, and signal "bias." ...

KDM5 inhibition/disruption selectively induces R-loop-mediated DNA damage and innate immune activation in breast cancer cells, while sparing normal cells, unveiling a tumor-specific therapeutic ...

Researchers improved an enzyme, rlevblg1, which breaks down sugar into gut-healthy fructooligosaccharides. By attaching it to ...