Former President Barack Obama's favorite Chicago pizza place doesn't serve deep dish, but that's okay; it serves the other Chicago-style pizza Obama prefers.

A new study shows the number of people dying from cancer is on the decline, but more women and younger adults are being diagnosed with it. The annual report from the American Cancer Society, published Thursday in CA: A Cancer Journal for Clinicians,

U.S. Supreme Court justices unanimously ruled that the law requiring the sale of the app did not violate the First Amendment protection against government abridgment of free speech.

Mayor Brandon Johnson’s new city guidance on dealing with Immigrations and Customs Enforcement is blasted by a Chicago alderman trying to remove dangerous criminals.

Some developers and contractors are taking a wait-and-see approach, while others are scrambling to prepare for taxes that could increase prices.

Chicago police are looking for two suspects in connection to the murder of an Army veteran in Little Village more than two years ago. The victim's father spoke out Thursday after the latest break in the case.

The new Chicago Board of Education was sworn in while the Chicago Teachers Union President Stacy Davis Gates calls for a contract settlement.

As a cold blast of Arctic air looms next week, Amtrak has canceled multiple trains either originating or ending in Chicago.

Five Walgreens stores will shutter their doors in Chicago next month, as part of a nationwide series of closures announced by the drugstore chain last year.

I’m an Orthodox rabbi, I’m a Zionist rabbi, I need you to know that,’” he recalled telling the Chicago-area Muslim religious leaders. “And they said, ‘We understand. We would like you ...