Acyl-CoA thioesterases (ACOTs) are a family of enzymes that catalyse the hydrolysis of acyl-CoA molecules into free fatty acids and coenzyme A (CoA). This reaction is a critical control point in lipid ...
Metformin is a widely used first-line therapy for type 2 diabetes, and studies increasingly point to its protective effects on the kidney. However, the mechanisms underlying metformin's renal benefits ...
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