A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for ...

A study published in Science reveals a cellular mechanism involved in the inheritance of genetic mutations. The study also ...

CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

Most human DNA is packaged in the chromosomes within a cell’s nucleus. But our cells also have what is called mitochondrial DNA (mtDNA). The mitochondria are small structures located in the fluid ...

Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides into mitochondrial DNA (mtDNA) initiates an inflammatory cascade.

Almost every type of human cell is powered by mitochondria, bean-shaped organelles that use oxygen to synthesize usable energy.* These structures evolved billions of years ago from free-swimming ...

One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

Back in the 19 th century, as the US grappled with the aftermath of the Civil War, Jesse James, leader of a notorious gang of outlaws, rose to prominence. He robbed banks and trains for over a decade ...