Endocrine therapy typically slows cell cycle progression by reducing cyclin D1, which partners with CDK4/6 to promote cell ...

When cancer progresses on endocrine therapy, the next step is likely either a biopsy to gather tissue for testing or a liquid ...

FMC-242 is a potentially best-in-class covalent allosteric inhibitor that breaks the interaction between PI3Kα and RAS, ...

What Are Eccentric and Concentric Contractions? Eccentric contractions occur when a muscle lengthens under load, such as ...

This review systematically examines the potential of spices and culinary herbs (e.g., turmeric, garlic, ginger) for breast cancer (BC) prevention and treatment, elucidating their underlying mechanisms ...

New research has uncovered a mechanism for parents to pass down longevity, to their progeny, via changes to their lysosome ...

Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting ...