Enter tRNA. "Transfer RNAs are ancient molecules," said Gustavo Caetano-Anollés of the University of Illinois at Urbana-Champaign. "They're molecular fossils." Caetano-Anollés and his colleague ...

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

For disorders driven by a known genetic component, research understandably focuses on developing a drug targeting that genetic signature. When that works, the outcome benefits patients but the end ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation, which ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Transfer RNA, more commonly referred to as tRNA, is well known for its key role in translating genetic material into protein. Recent discoveries about fragments of tRNA, which scientists had ...

Professor Zhou's research group focuses on developing and applying new technologies to visualize spatial and temporal distributions of chemical modifications in the mammalian transcriptome at ...

An abnormal epigenetic modification of RNA could be related to senescence and aging disorders, pointing towards the enzyme methyltransferase-like 1 (METTL1) as a potential therapeutic target.

Initially dismissed as a wealthy and frivolous socialite, Charles Swann in Marcel Proust’s “In Search of Lost Time” eventually transforms from a minor figure to an important one. Were biology a novel, ...

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...

Pyrrolysine is an important component of methyltransferase enzymes, which the archaea use to metabolize methylamine in the environment. “The need for that metabolism and availability of the machinery ...