Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.
Van Andel Institute scientists develop technique for high-resolution single cell epigenetic analysis
GRAND RAPIDS, Mich. (July 15, 2025) — Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help ...
Different cell types typically express unique genes to help them differentiate into their assigned roles—skin cells express genes for skin while liver cells express genes for liver and so on. However, ...
The diversity of unicellular eukaryotes covered in the study, with their nucleus (blue) and microtubule cytoskeleton (magenta) stained. These organisms are so distantly related to each other as they ...
Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...
The field of immunogerontology investigates age-associated declines in immune function, particularly focusing on the reduced lymphoid potential of ...
Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...
Scientists say they have found a pattern of so-called epigenetic 'marks' in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a ...
All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is ...
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