NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New York Giants and Chicago Bears.

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

The New York Giants host the San Francisco 49ers at MetLife Stadium in East Rutherford, New Jersey, this Sunday at 1:00 p.m. EDT.

Since the injury avalanche hit the 49ers have managed to keep their heads above water and not suffer any bad losses. After losing in Week 8 to the Houston Texans on the road, the spotlight gets a little brighter for a group that has been pushed into bigger roles with a handful of injuries for San Francisco on both sides of the ball.

The Eagles are 6-2 and once again look like one of the best teams in the NFL after a dominating 38-20 win over the New York Giants at Lincoln Financial Field on Sunday. A.J. Brown was ruled out, paving the way for Saquon Barkley to have his first 100-yard game of the season,

With a Week 9 game between the New York Giants and San Francisco 49ers on tap, Giants Wire goes behind enemy lines with Niners Wire.