Get the opening NFL Week 10 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Nov. 6, 2025.

In Week 10, the Kansas City Chiefs are scheduled for the annual bye week. All three of the AFC West foes will be playing, however. The Broncos are coming off an 18-15 victory on the road over the Houston Texans in Week 9. The Raiders came up short in a 30-29 overtime loss to the Jacksonville Jaguars on Sunday.

T he Chicago Bears and the New York Giants will meet for Week 10 on Sunday, November 9, at Noon (CT) from the Windy City, and right now, our partners at FanDuel Sportsbook have th

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 9 on a sizzling 45-28 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

A few contenders made statement wins on Sunday in Week 8, as the Philadelphia Eagles and Bufflo Bills both won by double digits, improving their Super Bowl odds

Week 10 of the college football season kicks off Tuesday night with two games: one featuring a Conference USA contender and the other highlighting the Sun Belt 's top dog. Betting odds: Kennesaw State (-10.5), O/U 51.5

After two bad weeks, it's back to the winning ways for me with my NFL picks. I went 9-4 against the spread last week and 10-3 straight up. That's my kind of week. It ups my season records to 64-57 ATS and 86-34-1 straight up.

A ton of teams were on the bye in Week 8 of the NFL season, but that didn’t stop a major shakeup in the odds to win the NFL MVP compared to last Monday. While K