When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

The MMP of CD8 + T cells could serve as a valuable predictor of BI and ACLF within 90 days in cirrhotic patients. The study was recently published in the Journal of Clinical and Translational ...

A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast ...

A new study offers a fresh perspective on the role of sodium in mitochondrial physiology and points the way to future research into the relationship between complex I disorders and a host of neuronal ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats. These molecules undergo further modification in ...

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, and David ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca 2+ signaling. In particular, mitochondrial Ca ...

Discover how CKMT2 controls energy balance and mitochondrial health in skeletal muscles, revealing a new link between metabolism and type 2 diabetes management. Study: Decreased mitochondrial creatine ...

CyDENT represents a revolutionary advancement in genetic modification, facilitating CRISPR-free base editing within mitochondria and chloroplasts. This breakthrough technology heralds a new era in ...