An international research team involving the working group of biophysicist Dr. Manuel Etzkorn from Heinrich Heine University Düsseldorf (HHU) has developed an approach for using NMR spectrometry to ...

In the intricate landscape of human biochemistry, few processes wield as much influence over overall health as methylation. This fundamental cellular mechanism, involving the transfer of methyl groups ...

When researchers began to study the human genome, the focus was on genes that code for protein. Proteins are crucial parts of nearly every aspect of biology, and they are very relevant to human ...

It turns out that methyl groups on DNA are more than genetic cobwebs; the chemical tags actively silence genes, making them potential therapeutic targets. A new generation of CRISPR technology ...

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...