Tsukuba, Japan - Many studies have attempted to identify a single transcription factor that can induce formation of mesoderm, an early layer in embryonic development, without help from other cellular ...

Early steps for cardiac specification are problematic for the study of mammalian embryos, which has favored using pluripotent cells that recapitulate cardiac myogenesis. Furthermore, circuits ...

Corals first appeared on earth nearly half a billion years ago during the Cambrian Period of the Paleozoic Era. The ancient Greek philosopher Aristotle categorized corals as zoophyta, or ...

Segmentation of the vertebrate body is first established during embryogenesis by the periodic formation of pairs of somites — for example, every 120 minutes in mouse, 90 minutes in chicken and 30 ...

Dlc1 deletion affects cardiac differentiation in mouse embryonic stem cells by activating the canonical Wnt pathway ...

Tadahiro Iimura, Ph.D., senior research associate in the Pourquié Lab, is the lead author on a paper challenging controversial theories about the mode of formation of the vertebral column precursor, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 22 (May 31, 2011), pp. 9160-9165 (6 pages) FGF signaling is one of the few cell—cell signaling pathways ...

How do cells turn into organs? During embryonic development, three germ layers form, known as the endoderm, the mesoderm, and the ectoderm. These germ layers give rise to different parts of the ...

In a study of over 50 transcription factors, Tbx6 alone was able to stimulate mesoderm formation in laboratory-grown stem cells, and could cause those stem cells to become cardiovascular or ...