The glycosylation mechanisms in Streptococcus bacterial adhesins constitute a complex post-translational modification system that is vital for bacterial adhesion, biofilm formation, and pathogenicity.

While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...

Scientists have discovered that depression can be driven by abnormal sugar modifications on proteins in the brain, offering a new molecular pathway for understanding the disorder.

Depression is a serious disorder that disrupts daily life through lethargy, sleep disturbance, and social withdrawal, and ...

Glycans are sugar chains that bind to cells through proteins or lipids, influencing their chemical properties. These complex, often branched structures stabilize the extracellular domains of cells and ...

Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain. Our guts are home to trillions of bacteria, and ...

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease. A new study from EMBL Heidelberg ...

Chronic stress disrupts O-glycans in the mouse prefrontal cortex. The findings open new possibilities for depression treatment.

Scientists discover chronic stress disrupts brain sugar molecules, causing depression through mechanisms current ...

Two Ohio University Ph.D. students recently showcased their research at the 2025 International Conference on Plant Cell Wall ...

The main text details the experimental design, including the generation of CO and CPO ADAMTS13 variants using different algorithms, and the evaluation of these variants in terms of protein expression, ...