Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Conventional light microscopy has been instrumental for the study of cells and microorganisms; fluorescence microscopy has enabled visualization of even smaller cell features by selectively adding ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

Fluorescence nanoscopy has transformed our ability to visualize and discover biological structures. In recent years, ultraprecise single-molecule localization techniques such as MINFLUX and RASTMIN ...

Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice. These investigations require monitoring brain activity ...

The Sutter NAN ™ is a focusing nosepiece microscope designed for electrophysiology. The microscope frame is a reimagined version of Sutter's highly stable and adjustable MT-70 manipulator gantry ...