Intraosseous (IO) vascular access has emerged as a critical technique in emergency medicine, offering rapid and reliable delivery of fluids and medications when traditional intravenous (IV) access ...

In the PARAMEDIC-3 trial conducted in the U.K., the 30-day survival rate was 4.5% when the first attempt at access was intraosseous and 5.1% with the intravenous-first strategy (adjusted OR 0.94, 95% ...

For patients experiencing out-of-hospital cardiac arrest and needing drugs, a strategy of paramedics attempting intraosseous access first does not improve survival. A pragmatic, randomised PARAMEDIC-3 ...

One approach to earlier administration of epinephrine during OHCA is via the intraosseous route, as this can be performed quickly in the field. In our laboratory, Zuercher et al. recently found that ...