This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. The human genome is a vast landscape, with less than 2% of its sequence encoding proteins. For many years, ...

Image Caption: Technologies evolved related to the Human Genome Project. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

In a keynote talk during GEN’s “The State of CRISPR & Genome Editing” virtual summit, originally broadcast on June 11, 2025, Neville Sanjana, PhD, Core Faculty Member at the New York Genome Center and ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

Rapid advances in sequencing technologies have transformed our ability to diagnose human genetic disorders, yet many patients still lack a molecular ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

We mapped the human genome decades ago, but most of it is still a black box. Now, UNSW scientists have developed a tool to peer inside and what they find could reshape how we think about disease.

Sequencing nearly half a million genomes, researchers show that most additive genetic influences on height, lipids, and other complex traits are now directly measurable, while pinpointing ultra-rare ...

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we ...