Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

Hepatocytes are epithelial cells found in the liver. These specialized cells make up almost 80% of the human liver’s total mass, fulfilling a wide variety of metabolic, secretory, and endocrine tasks.

Researchers from the University of Illinois Urbana-Champaign have published data from a study designed to assess the role of serine-arginine-rich splicing factor 1 (SRSF1) in hepatocyte function and ...

What am I looking at? This is a single human hepatocyte. Its two nuclei are in blue (1). The other colors in this image are stains of the actin protein and are depth-coded, with red being the closest ...

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...