Frailty was tied to a higher risk of future dementia in older adults. Trajectories rose more rapidly 4 to 9 years before dementia onset. The analysis included 30,000 participants in the U.S. and U.K.

Physical frailty is strongly associated with an increased dementia risk in older adults, and according to researchers, the link may be causal. In an analysis of nearly half a million UK Biobank ...

The primary endpoint included improvement in any of the five frailty phenotype criteria, such as unintentional weight loss or exhaustion, or a one-point increase in the Short Physical Performance ...