Dr. Aaronson answers the question: 'Aldosterone Antagonist Side Effects?' — -- Question: What are the benefits and side effects of an aldosterone antagonist? Answer: Thanks to research led by Dr.

A subgroup analysis of data from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) shows that the beneficial effects of the selective aldosterone ...

Aldosterone sends sodium and water into the bloodstream, which can increase your blood volume and blood pressure. Besides the ...

Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension. In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated systolic blood ...

Type 2 diabetes (T2D) incidence continues to rise among African Americans (AAs). However, it has been observed to plateau among non-Hispanic whites (NHWs). Moreover, T2D-associated mortality and ...

Aldosterone escape and non-ACE pathways for angiotensin II production may explain, at least in part, the continued high mortality rates in heart failure patients despite the advances made in ...

Lorundrostat, a novel aldosterone synthase inhibitor, reduces blood pressure among patients with uncontrolled hypertension on at least two drugs, according to results from the phase II Target-HTN ...

MADRID, Spain—Baxdrostat (AstraZeneca), an investigational aldosterone synthase inhibitor, provides substantial reductions in blood pressure when added to background therapy in patients with ...

In a phase 2 trial, an investigational drug that inhibits aldosterone synthase significantly lowered albuminuria in patients with or without type 2 diabetes. PHILADELPHIA—A novel selective aldosterone ...

AstraZeneca (NASDAQ:AZN) announced on Tuesday that a blood pressure therapy it acquired through its 2023 acquisition of ...