The puzzle seems impossible: take a three-billion-letter code and predict what happens if you swap a single letter. The code we’re talking about—the human genome—stores most of its instructions in ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

A team of researchers at a Berkeley-based startup called Profluent say they’ve used generative AI technologies to edit human DNA. Their goal is to produce gene editors that are more efficient and ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...