Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Mutations in the GNAO1 gene can lead to severe neurological disorders, leading to treatment-resistant epilepsy, developmental delay and movement disorders in children. Zinc supplementation has emerged ...

The calcium-regulated protein drug (green) and tumor cell receptors (red) have bonded and internalization is underway, 40 seconds after administration. Cancer-fighting antibody drugs are designed to ...

The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...

The nonapeptide Oxytocin is a cyclic nine-amino‐acid peptide that has long been studied for its possible roles in ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

Chimeric antigen receptor (CAR) T cell-based therapy has greatly improved cancer treatment, especially for hematologic cancers. 1 By providing T cells with synthetic receptors that target tumor ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...