A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be ...

Bioengineers at Queen Mary University of London have taken a significant step forward in the development of laboratory-based models of human tissues that may be used as alternatives to animal testing.

3D surface of the fruit fly wing disc before (left) and after (right) eversion. Highlighted in blue is the pouch region, which transforms from a radially symmetric dome into a curved fold by ...