Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be ...

Pyruvate kinase PEP + ADP Pyruvate + ATP Glycolysis Catalyzes last step of glycolysis; irreversible reaction. Enzyme activated by feed forward action fructose 1,6-bisphosphate; synthesis stimulated by ...

Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. Many tumor cells exhibit rapid glucose consumption, with most of the glucose-derived ...

Glycolysis shows different patterns of operation and different control steps, depending on whether the level of Crassulacean acid metabolism (CAM) is low or high in the leaves of Kalanchoe ...

Many years have been spent trying to develop a drug that can prevent metastasis. Yet, up until now, cancer has remained a lethal and untreatable disease. However, doctors have recently made a ...

PD-1 blockade with camrelizumab after chemoradiotherapy in nasopharyngeal carcinoma. This is an ASCO Meeting Abstract from the ASCO Breakthrough: A Global Summit for Oncology Innovators. This abstract ...

Researchers have long believed that neurons rely on glucose nearly entirely for fuel. The brain’s enormous energy ...

Dogma says that brain metabolism slows down with age: Blood flow, and the total demand for fuel in the form of glucose, decline with passing years. A new study shows that waning glucose uptake is just ...

What is Gibbs free energy? Josiah Willard Gibbs, an American mathematician, first described Gibbs free energy in the 1870s. According to Gibbs, free energy is the total energy of a system that is ...