The drug targets the overgrowth of synovial cells and inflammatory components that drive tumor development and joint ...

Deciphera Pharmaceuticals, LLC, a biopharmaceutical company focused on discovering, developing, and commercializing important ...

Tenosynovial giant cell tumors are a rare, locally aggressive neoplasm that is driven by an overexpression of colony-stimulating factor 1 (CSF1), a genetic anomaly which secretes a protein into the ...

BioWorld Content on 'tenosynovial giant cell tumors'Synox Therapeutics Ltd. has raised $75 million in a series B round to fund phase III development of emactuzumab, an antibody in-licensed from Roche ...

Romvimza, a drug for treating tenosynovial giant cell tumor, was initially developed by Deciphera Pharmaceuticals. Last year, Ono Pharmaceutical acquired Deciphera to build up its oncology ...

The Food and Drug Administration (FDA) has approved Romvimza ™ (vimseltinib) for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical ...

Discover Vimseltinib, the newly FDA-approved treatment for tenosynovial giant cell tumor (TGCT). Learn about its benefits, safety, and impact on patient quality of life.

Source Reference: Gelderblom H, et al "Vimseltinib versus placebo for tenosynovial giant cell tumour (MOTION): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial" Lancet ...

Tenosynovial Giant Cell Tumors (TGCT) are rare, typically benign tumors that occur in the joint lining, tendon sheaths, or bursae. They can cause pain, swelling, and restricted movement in the ...

Tenosynovial giant cell tumor is a rare condition of the joint that can cause symptoms like pain, swelling, and limited movement. Exercise tips from a physical therapist may help you maintain ...

A new dosing regimen for Turalio ® (pexidartinib) is now available for the treatment of adults with symptomatic tenosynovial giant cell tumor associated with severe morbidity or functional ...

An investigational drug, PLX3397 (Plexxikon, Daiichi Sankyo), has shown prolonged tumor regression in patients with tenosynovial giant cell tumor (TGCT), a rare disorder of the joints that leaves ...